When Brooks gets out of prison in Shawshank and realizes how much he depended on the prison and became "institutionalized". You know the rest... right in the feels.
Ah man, yeah this one gets me. I am one of those that really gets the feels with music. Call me a wuss, but Les Miserables gets me. Green Mile. Any involving a father and son (edit: add), which reminds me of John Q and of course:
I only watched it once. Cannot watch again. The end of Marley and Me. I've had to do that too many times, I don't want to see it on TV while my best friend is laying in my lap.
Pursuit of Happiness final scene where they give him the job. Or Seven Pounds opening scene where he yells at Woody Harrelson. Stupid Will Smith.
Man, if THOSE dog movie got y'all crying, there's an episode of Futurama that will KILL you. I don't even like Futurama particularly, I just remember an episode about Fry's dog - that was the ONLY TV/movie moment that made me cry. House of Sound & Fog made me let out a big - dheymmmmmmmmmm - though.
Waiting for Apollo 13 to radio back whilst descending Earths atmosphere. I think its the music that gets me though. Damn James Horner.
That Futurama episode gets me every time. Couple other tv episodes that still get me... MASH - When Henry Blake dies The West Wing - when John Spencer had passed and they had to write it in for Leo McGarry to die of a heart attack